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相关概念视频

Disorders of the Male Reproductive System01:20

Disorders of the Male Reproductive System

Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra. Symptoms...
Cancer Vaccines01:30

Cancer Vaccines

Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
Cancer Survival Analysis01:21

Cancer Survival Analysis

Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
mTOR Signaling and Cancer Progression03:03

mTOR Signaling and Cancer Progression

The mammalian target of rapamycin or mTOR protein was discovered in 1994 due to its direct interaction with rapamycin. The protein gets its name from a yeast homolog called TOR. The mTOR protein complex in mammalian cells plays a major role in balancing anabolic processes such as the synthesis of proteins, lipids, and nucleotides and catabolic processes, such as autophagy in response to environmental cues, such as availability of nutrients and growth factors.
The mTOR pathway or the...

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相关实验视频

Updated: Jul 5, 2026

A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer
07:25

A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer

Published on: March 6, 2018

前列腺癌是什么意思 前列腺癌是什么意思

Jan-Erik Damber1, Gunnar Aus

  • 1Department of Urology, Sahlgrenska University Hospital, Gothenburg, Sweden.

Lancet (London, England)
|May 20, 2008
PubMed
概括
此摘要是机器生成的。

前列腺癌是一种常见的诊断,但查的增加意味着发现了许多低风险病例. 大多数被诊断为前列腺癌的病例不会危及生命,这表明过度诊断是一个问题.

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miRNA Expression Analyses in Prostate Cancer Clinical Tissues
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miRNA Expression Analyses in Prostate Cancer Clinical Tissues

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Pre-clinical Orthotopic Murine Model of Human Prostate Cancer
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Pre-clinical Orthotopic Murine Model of Human Prostate Cancer

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Last Updated: Jul 5, 2026

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07:25

A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer

Published on: March 6, 2018

miRNA Expression Analyses in Prostate Cancer Clinical Tissues
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miRNA Expression Analyses in Prostate Cancer Clinical Tissues

Published on: September 8, 2015

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Pre-clinical Orthotopic Murine Model of Human Prostate Cancer

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科学领域:

  • 在瘤学瘤学.
  • 泌尿器科 泌尿器科 泌尿器科 泌尿器科
  • 公共卫生 公共卫生

背景情况:

  • 前列腺癌是全球第二常诊断的癌症,也是全球男性癌症死亡的第三大原因.
  • 一个积极的家族史是一个重要的风险因素,与年龄和种族一起.
  • 目前的治疗方法,如抗雄激素剥夺,短期有效,但往往导致无法治愈的复发.

研究的目的:

  • 分析前列腺癌发病率和死亡率的趋势.
  • 评估查和诊断进步的影响.
  • 评估低风险前列腺癌的进展率.

主要方法:

  • 对前列腺癌发病率和死亡率的流行病学数据的审查.
  • 分析影响诊断的因素,包括PSA查和活检技术.
  • 评估晚期前列腺癌治疗结果和复发率.

主要成果:

  • 由于查和改进的诊断,前列腺癌发病率大幅上升.
  • 死亡率趋势不那么明显,一些国家显示死亡率稳定或下降.
  • 一小部分被诊断的低风险前列腺癌进展到危及生命的阶段.

结论:

  • 发病率上升和死亡率稳定/下降之间的差异表明低风险前列腺癌的过度诊断.
  • 查和诊断的改进增加了检测,但不一定会相应地改善生存结果.
  • 需要进一步的研究来区分惰性的前列腺癌和积极的前列腺癌,以优化治疗策略.