前列腺癌是什么意思 前列腺癌是什么意思
1Department of Urology, Sahlgrenska University Hospital, Gothenburg, Sweden.
Lancet (London, England)
|May 20, 2008
概括
前列腺癌是一种常见的诊断,但查的增加意味着发现了许多低风险病例. 大多数被诊断为前列腺癌的病例不会危及生命,这表明过度诊断是一个问题.
科学领域:
- 在瘤学瘤学.
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 公共卫生 公共卫生
背景情况:
- 前列腺癌是全球第二常诊断的癌症,也是全球男性癌症死亡的第三大原因.
- 一个积极的家族史是一个重要的风险因素,与年龄和种族一起.
- 目前的治疗方法,如抗雄激素剥夺,短期有效,但往往导致无法治愈的复发.
研究的目的:
- 分析前列腺癌发病率和死亡率的趋势.
- 评估查和诊断进步的影响.
- 评估低风险前列腺癌的进展率.
主要方法:
- 对前列腺癌发病率和死亡率的流行病学数据的审查.
- 分析影响诊断的因素,包括PSA查和活检技术.
- 评估晚期前列腺癌治疗结果和复发率.
主要成果:
- 由于查和改进的诊断,前列腺癌发病率大幅上升.
- 死亡率趋势不那么明显,一些国家显示死亡率稳定或下降.
- 一小部分被诊断的低风险前列腺癌进展到危及生命的阶段.
结论:
- 发病率上升和死亡率稳定/下降之间的差异表明低风险前列腺癌的过度诊断.
- 查和诊断的改进增加了检测,但不一定会相应地改善生存结果.
- 需要进一步的研究来区分惰性的前列腺癌和积极的前列腺癌,以优化治疗策略.
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