一种新的方法来表达左心室质量相对于儿童的身体大小
Bethany J Foster1, Andrew S Mackie, Mark Mitsnefes
1Department of Pediatrics, Montreal Children's Hospital, Hospital, McGill University, Montreal, Quebec H3H 1P3, Canada. beth.foster@muhc.mcgill.ca
Circulation
|May 21, 2008
概括
左心室质量对高度百分曲线为儿童诊断左心室缩 (LVH) 提供了一种稳定的方法,在各种参考人群中表现优于传统的左心室质量指数 (LVMI).
科学领域:
- 儿童心脏病学 儿童心脏病学
- 生物医学工程 生物医学工程
- 增长和发展 增长和发展
背景情况:
- 儿童的左心室缩 (LVH) 通常使用左心室质量指数 (LVMI) 超过第95个百分点来定义.
- 由于LVMI依赖于参考人群的身高分布,导致了变化,特别是在较小的儿童中,LVMI随身高的下降而增加.
研究的目的:
- 用百分曲线与传统的LVMI方法比较一种使用百分曲线的新型LV质量与体积大小规范化方法的有效性.
- 评估LVH分类在不同基准人群身高分布中的稳定性和可靠性.
主要方法:
- 在440名健康儿童和239名风险儿童中,通过M模式心声学评估左心室质量.
- 计算了LVMI,并使用Cole lambda-mu-sigma方法构建了LV质量对高度百分曲线.
- 风险儿童被用样本特定的LVMI百分位数和新型百分位曲线方法对LVH进行分类.
主要成果:
- 根据LV质量与身高的百分比方法,无论参考组的身高分布如何,LVH风险儿童的比例都得到了一致的估计.
- 相比之下,基于LVMI的LVH比例估计有很大差异,取决于所使用的特定参考人群.
- 百分点曲线方法在不同儿科群体的LVH分类中表现出更大的稳定性.
结论:
- 左心室质量对高度百分曲线提供了一种更强大和可靠的方法,用于在儿科患者群体中将LV质量与身体尺寸正常化.
- 这种新的方法克服了LVMI的局限性,为儿童的LVH提供了稳定的诊断工具.
相关概念视频
01:06Body Planes
Body planes in anatomy are imaginary flat surfaces used as reference points to divide the body into sections for anatomical study. These planes are essential for understanding the orientation, relationships, and spatial organization of anatomical structures.
The sagittal plane is the plane that divides the body or an organ vertically into right and left sides. If this vertical plane runs directly down the middle of the body resulting in equal division, it is called the midsagittal or median...
The sagittal plane is the plane that divides the body or an organ vertically into right and left sides. If this vertical plane runs directly down the middle of the body resulting in equal division, it is called the midsagittal or median...
01:03Centroid of a Body: Problem Solving
The centroid of a body is a crucial concept in engineering and physics. Finding the centroid of a body can help determine its stability, its balance point, and even its design. In this context, consider a thin wire bent in the form of a quarter circular arc. Polar coordinates are used to calculate the centroid. The wire is first divided into small differential elements of a length equal to the radius multiplied by the differential angle.
The x-coordinates and y-coordinates of each element's...
The x-coordinates and y-coordinates of each element's...
01:05Estimation of the Physical Quantities
On many occasions, physicists, other scientists, and engineers need to make estimates of a particular quantity. These are sometimes referred to as guesstimates, order-of-magnitude approximations, back-of-the-envelope calculations, or Fermi calculations. The physicist Enrico Fermi was famous for his ability to estimate various kinds of data with surprising precision. Estimating does not mean guessing a number or a formula at random. Instead, estimation means using prior experience and sound...
01:26Imbalances in Cardiac Output
The heart's primary function is to pump blood throughout the body, maintaining a balance between blood sent out (cardiac output) and blood returning (venous return). If this balance is disrupted, it can result in congestive heart failure (CHF), a severe condition where the heart becomes an inefficient pump, leading to inadequate blood circulation.
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send blood...
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send blood...