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Updated: Jul 11, 2026

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编码酵母脱枝酶的基因的分离和表征

K B Chapman1, J D Boeke

  • 1Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205.

Cell
|May 3, 1991
PubMed
概括

在DBR1基因的突变中断了内周转,并减少了酵母中的Ty1转化. DBR1基因编码了分支酶,对于切除的内核降解至关重要,但对细胞存活不至关重要.

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Yeasts are single-celled organisms, but unlike bacteria, they are eukaryotes (cells with a nucleus). Cell signaling in yeast is similar to signaling in other eukaryotic cells. A ligand, such as a protein or a small molecule released from a yeast cell, attaches to a receptor on the cell surface. The binding stimulates second-messenger kinases to activate or inactivate transcription factors that further regulate gene expression. Many of the yeast intracellular signaling cascades have similar...