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Updated: Jul 5, 2026

Characterization of Glycoproteins with the Immunoglobulin Fold by X-Ray Crystallography and Biophysical Techniques
08:58

Characterization of Glycoproteins with the Immunoglobulin Fold by X-Ray Crystallography and Biophysical Techniques

Published on: July 5, 2018

双功能CD22连接体使用多重体免疫球蛋白作为蛋白质支架,在B细胞上组装免疫复合体

Mary K O'Reilly1, Brian E Collins, Shoufa Han

  • 1Department of Chemical Physiology, The Scripps Research Institute, 10550 N. Torrey Pines Road, La Jolla, California 92037, USA.

Journal of the American Chemical Society
|May 29, 2008
PubMed
概括

研究人员使用抗体支架开发了一种合成分子,以向CD22 (B细胞调节器). 这种方法有效地在B细胞上组装复合物,显示了向B细胞恶性瘤的潜力.

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