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多种药物耐药性蛋白-1 影响氧化应激,内皮功能障碍和通过白血C4出口的动脉生成

Cornelius F H Mueller1, Kerstin Wassmann, Julian D Widder

  • 1Medizinische Klinik und Poliklinik II, Universitätsklinikum Bonn, Sigmund Freud Str 25, 53105 Bonn, Germany. cornelius.mueller@ukb.uni-bonn.de

Circulation
|May 29, 2008
PubMed
概括

多重耐药性蛋白-1 (MRP1) 和白血C4 (LTC4) 通过增加血管细胞中的氧化应激来促进动脉样硬化. 抑制MRP1或LTC4受体可以减少斑块形成并改善血管功能.

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