肥胖,行为生活方式因素以及急性冠状动脉事件的风险
Majken K Jensen1, Stephanie E Chiuve, Eric B Rimm
1Department of Clinical Epidemiology, Aarhus University Hospital, Sdr Skovvej 15, DK-9100 Aalborg, Denmark. mkj@dce.au.dk
Circulation
|June 11, 2008
概括
肥胖增加了急性冠状动脉综合征 (ACS) 的风险,但健康的生活方式选择,如体育活动和不吸烟可以减轻这种风险. 即使是肥胖的人也可以从更健康的习惯中受益.
科学领域:
- 心脏病学 心脏病学
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 肥胖,体育活动和急性冠状动脉综合征 (ACS) 风险之间的相互作用受到争论.
- 关于其他可修改的生活方式因素如何影响肥胖对ACS风险的影响,数据有限.
研究的目的:
- 研究肥胖和生活方式因素 (体育活动,吸烟,饮食) 对急性冠状动脉综合征 (ACS) 风险的综合影响.
主要方法:
- 来自丹麦饮食,癌症和健康研究中的54,783名成年人 (50-64岁) 的前性队列研究.
- 随访时间中位数为7.7年,记录了突发性急性冠状动脉综合征 (ACS) 病例.
- 多变量调整身体质量指数 (BMI),体力活动,吸烟和饮食模式.
主要成果:
- 体重指数的每一个单位的增加与5% (女性) 和7% (男性) 更高的ACS风险相关.
- 超重和肥胖增加了ACS风险,无论身体活动,吸烟状态或饮食遵守情况如何.
- 参与每周1-3,5小时体育活动的肥胖人群比久坐不动的肥胖人群有较低的ACS风险.
- 肥胖的非吸烟者比肥胖的吸烟者有较低的ACS风险.
- 坚持健康饮食降低了ACS风险,但肥胖个体与最健康的饮食与不健康的饮食之间的风险是相似的.
结论:
- 肥胖独立地增加了急性冠状动脉综合征 (ACS) 风险在不同的生活方式.
- 坚持健康的生活方式行为,包括体力活动和不吸烟,与降低ACS风险有关,即使在肥胖的人群中也是如此.
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