相关实验视频
Updated: Jul 4, 2026

06:09
Rapid Isolation of Single Cells from Mouse and Human Teeth
Published on: October 28, 2021
与刷牙和拔牙相关的细菌病
Peter B Lockhart1, Michael T Brennan, Howell C Sasser
1Department of Oral Medicine, Carolinas Medical Center, PO Box 32861, Charlotte, NC 28232-2861, USA. Peter.Lockhart@carolinashealthcare.org
Circulation
|June 11, 2008
概括
刷牙可能会比单一的牙提取带来更大的感染性内心炎 (IE) 细菌病的风险,尽管阿莫西西林的预防效果很好. 每日口腔卫生实践需要仔细考虑IE预防策略.
科学领域:
- 口腔微生物学 口腔微生物学
- 传染性疾病 传染性疾病
- 心脏病学 心脏病学
背景情况:
- 目前感染性内心炎 (IE) 预防指南考虑了牙科手术的细菌病.
- 刷牙是常见的口腔卫生活动,可能会显著增加IE风险.
研究的目的:
- 为了比较牙刷和单一牙提取之间的细菌病发率,持续时间,性质和大小.
- 评估阿莫西西林在单一牙拔除手术中的预防效果.
主要方法:
- 这是一项双盲,安慰剂控制的研究,涉及290名受试者.
- 随机化为牙刷,用阿莫西西林提取或用安慰剂提取.
- 在6个时间点收集的血液培养,以识别IE相关的细菌.
主要成果:
- 与IE相关的细菌病的累积发病率为23% (牙刷),33% (提取-阿莫西西林) 和60% (提取-安慰剂).
- 在干预后的组之间观察到细菌病的显著差异.
- 氨基显著减少了阳性细菌培养 (P<0.0001).
结论:
- 与单一的牙拔除相比,刷牙可能对IE风险较高的个体构成更大的细菌威胁.
- 阿莫西西林在减少牙提取所致细菌病的显著影响.
- 经常的口腔卫生实践需要对IE预防进行仔细评估.
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