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Updated: May 8, 2026

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SMAD蛋白质控制DROSHA介导的微RNA成熟过程

Brandi N Davis1, Aaron C Hilyard, Giorgio Lagna

  • 1Department of Biochemistry, Tufts University School of Medicine, Boston, Massachusetts 02111, USA.

Nature
|June 13, 2008
PubMed
概括

转化生长因子β (TGF-β) 和骨形态遗传蛋白 (BMP) 信号迅速增加微RNA-21 (miR-21) 水平. 这增强了血管光滑肌肉细胞收缩,通过降低PDCD4的调节,PDCD4是收缩基因的负调节器.

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