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通过TRAPP膜结合复合体激活Rab Ypt1p的结构基础

Yiying Cai1, Harvey F Chin, Darina Lazarova

  • 1Department of Cell Biology, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06520, USA.

Cell
|July 1, 2008
PubMed
概括

TRAPPI复合体通过稳定其核酸结合口袋来激活Ypt1p,这是膜融合前的关键步骤. 这种对Rab GTPase激活的结构洞察力为了解膜结合提供了一个分子框架.

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