酒精隔膜切除用于阻塞性多变性心肌病的结果
Paul Sorajja1, Uma Valeti, Rick A Nishimura
1Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic College of Medicine, Rochester, MN 55905, USA. paul.sorajja@mayo.edu
Circulation
|July 2, 2008
概括
酒精隔膜切除在经验丰富的中心有效治疗阻塞性缩性心肌病症状,尽管并发症率高于肌切除术. 年轻的患者可能会从肌切除术中获得更多的好处,以缓解症状.
科学领域:
- 心脏病学 心脏病学
- 干预心脏病学 干预心脏病学
- 心脏外科手术 心脏外科手术
背景情况:
- 酒精隔膜切除治疗药物耐药性过度缩性心肌病的临床有效性尚未得到充分证实.
- 这项研究评估了酒精隔膜切除在专业的缩性心肌病中心的结果.
研究的目的:
- 评估酒精隔膜切除在患有阻塞性多变性心肌病的患者中的疗效和安全性.
- 为了比较 septal myectomy 的结果.
主要方法:
- 对138名经过酒精隔膜切除 (1998-2006) 的患者进行了回顾性分析.
- 与接受隔膜肌切除术的年龄和性别匹配的患者进行比较.
- 评估手术并发症,死亡率和症状的解决.
主要成果:
- 酒精隔膜切除的并发症率较高 (1.4%的死亡,20%的起器),而不是肌切除 (5%).
- 没有死亡的四年生存率为88.0%,类似于肌切除术.
- 51%的患者无症状,但肌切除术为65岁以下的患者提供了更好的症状解决.
结论:
- 酒精隔膜切除在经验丰富的中心进行时,有效缓解阻塞性缩性心肌病的症状.
- 切除术的手术并发症率超过了肌切除术的情况.
- 在较年轻的患者 (<=65岁) 中,肌肉切除可能对症状的缓解更为优越.
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