一种重组化学毒素对快速增殖的血管光滑肌细胞的细胞毒性作用

S E Epstein1, C B Siegall, S Biro

  • 1Cardiology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892.

Circulation
|August 1, 1991
PubMed
概括

这项研究开发了一种仿真毒素,TGF alpha-PE40,通过与表皮生长因子 (EGF) 受体结合,选择性地向并杀死快速增殖的光滑肌细胞 (SMC). 这种方法显示了通过消除有问题的SMCs来治疗像回症这样的疾病的潜力.

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