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Updated: Jul 3, 2026

A Strategy to Identify de Novo Mutations in Common Disorders such as Autism and Schizophrenia
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Published on: June 15, 2011

通过追踪最近的共同祖先来识别自闭症位点和基因.

Eric M Morrow1, Seung-Yun Yoo, Steven W Flavell

  • 1Division of Genetics, Children's Hospital Boston and Harvard Medical School, Boston, MA 02115, USA.

Science (New York, N.Y.)
|July 16, 2008
PubMed
概括

这项研究使用了家庭中的同卵性映射来识别自闭症谱系障碍的遗传原因. 像PCDH10和DIA1这样的关键基因被卷入其中,这表明神经活动中的基因表达改变是一种常见的自闭症机制.

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