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Updated: Jul 3, 2026

In Vitro Differentiation of Naive CD4+ T Cells into Pathogenic Th17 Cells in Mouse
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Published on: October 25, 2024

异常的17型对缺乏T-bet和eomesodermin的CD8+T细胞的病毒感染的反应

Andrew M Intlekofer1, Arnob Banerjee, Naofumi Takemoto

  • 1Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, PA 19104, USA.

Science (New York, N.Y.)
|July 19, 2008
PubMed
概括

转录因子T-bet和eomesodermin (Eomes) 对于CD8+ T细胞成为细胞毒杀手对抗细胞内病原体至关重要. 没有它们,CD8+ T细胞会促进有害的炎症,而不是有效的病毒防御.

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