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Circadian Entrainment of Drosophila Melanogaster
Published on: June 3, 2020
密码色调解了Drosophila中依赖光的磁敏性
Robert J Gegear1, Amy Casselman, Scott Waddell
1Department of Neurobiology, University of Massachusetts Medical School, Worcester, Massachusetts 01605, USA.
Nature
|July 22, 2008
概括
果使用一种称为加密色 (Cry) 的光敏感蛋白质进行磁感应. 阻断蓝光会破坏这种能力,表明哭泣.
科学领域:
- 动物行为 动物行为
- 生物物理学的生物物理.
- 遗传学 遗传学 是一个
背景情况:
- 许多动物使用地球的磁场来导航,但潜在的生物物理机制仍然不清楚.
- 一个领先的假设表明,磁感受涉及光感受器中依赖光的化学反应.
- 负责磁感应的特定光受体在任何物种中都尚未确定.
研究的目的:
- 为了研究加密色素 (Cry) 在Drosophila melanogaster中依赖光的磁敏行为中的作用.
- 为了确定加密色是摄影受体介导磁场感知在.
主要方法:
- 使用二进制选择设置进行行为分析,以测试野生类型和加密色素缺乏 (cry(0),cry(b)) Drosophila.
- 对光波长的操纵,特别是阻断紫外线-A/蓝光 (<420 nm) 对于加密染色激活至关重要.
- 在不同的光线条件下对磁场的天真和训练有素反应的评估.
主要成果:
- 野生类型的在全谱光线 (300-700 nm) 下表现出显著的磁感应反应.
- 当紫外线A/蓝光 (<420nm) 被阻断时,野生类型的磁感受性被废除了.
- 缺乏加密色素的 (cry(0),cry(b)) 在全光谱光下没有显示任何磁性反应.
- 密码颜色依赖的磁敏度是独立于功能性昼夜钟的.
结论:
- 密码色 (Cry) 对于Drosophila melanogaster的依赖光的磁敏反应至关重要.
- 这项研究为任何动物的基于加密色的磁传感系统提供了第一个遗传证据.
- 这些发现支持了加密色作为磁受体的假设,调解磁方向.
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