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在血管损伤后的neointima形成中对p38基因激活蛋白激酶活性的要求

Brandon M Proctor1, Xiaohua Jin, Traian S Lupu

  • 1Center for Cardiovascular Research, Department of Medicine, Washington University, St. Louis, School of Medicine, ST. Louis, Mo., USA.

Circulation
|July 23, 2008
PubMed
概括

血管光滑肌细胞p38alpha MAPK激活对于血管塑性手术后的neointimal病变形成至关重要. 抑制这种途径可以防止病变的发展,并减少相关的细胞增殖和DNA复制.

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