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病原体蛋白 EspF(U) 通过模仿和多价值性劫持了actin聚合.

Nathan A Sallee1, Gonzalo M Rivera, John E Dueber

  • 1Graduate Program in Chemistry and Chemical Biology, University of California, San Francisco, 600 16th Street, San Francisco, California 94158, USA.

Nature
|July 25, 2008
PubMed
概括

肠道出血性大肠杆菌使用 EspF(U) 蛋白来触发宿主细胞中的行为基脚的形成. 这种蛋白质独特地模仿了一个内部的N-WASP元素,而不是CDC42,以激活细菌附着的actin聚合.

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