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Updated: May 5, 2026

Monitoring the Assembly of a Secreted Bacterial Virulence Factor Using Site-specific Crosslinking
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通过输血性大肠杆菌效应体EspF的WASP激活的结构机制 (U)

Hui-Chun Cheng1, Brian M Skehan, Kenneth G Campellone

  • 1Department of Biochemistry and Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.

Nature
|July 25, 2008
PubMed
概括

肠出血性大肠杆菌 (EHEC) 通过注射 EspF (U) 蛋白质来劫持宿主细胞的活性. 这种蛋白质结合并激活威斯科特-阿尔德里希综合征蛋白 (WASP) 家族成员,控制感染期间的活性蛋白组合.

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