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Updated: Apr 15, 2026

Identification of Inositol Phosphate or Phosphoinositide Interacting Proteins by Affinity Chromatography Coupled to Western Blot or Mass Spectrometry
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Identification of Inositol Phosphate or Phosphoinositide Interacting Proteins by Affinity Chromatography Coupled to Western Blot or Mass Spectrometry

Published on: July 26, 2019

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Epac2与循环AMP类似物和RAP1B复合体中的结构

Holger Rehmann1, Ernesto Arias-Palomo, Michael A Hadders

  • 1Department of Physiological Chemistry, Centre for Biomedical Genetics and Cancer Genomics Centre, University Medical Center, Universiteitsweg 100, 3584 CG Utrecht, The Netherlands. h.rehmann@UMCutrecht.nl

Nature
|July 29, 2008
PubMed
概括

由cAMP激活的epac蛋白调节细胞粘附和胰岛素分泌. 结构分析揭示了cAMP结合如何改变Epac2形状,使Rap蛋白相互作用成为可能.

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