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Updated: Jul 3, 2026

Monitoring Cell-autonomous Circadian Clock Rhythms of Gene Expression Using Luciferase Bioluminescence Reporters
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Published on: September 27, 2012

SIRT1通过PER2脱乙化调节昼夜钟基因表达

Gad Asher1, David Gatfield, Markus Stratmann

  • 1Department of Molecular Biology, Sciences III, University of Geneva, 30, Quai Ernest Ansermet, CH-1211 Geneva-4, Switzerland.

Cell
|July 30, 2008
PubMed
概括

蛋白脱乙酶SIRT1对于昼夜节律转录至关重要. 它通过与CLOCK-BMAL1相互作用并促进PER2降解来调节核心时钟基因,将新陈代谢与身体联系起来.

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