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阿波利波蛋白CIII将高脂血症与血管内皮细胞功能障碍联系在一起

Akio Kawakami1, Mizuko Osaka, Mariko Tani

  • 1Department of Geriatrics and Vascular Medicine, Life Science and Bioethics Research Center, Tokyo Medical and Dental University, Tokyo, Japan. kawakami.vasc@tmd.ac.jp

Circulation
|July 30, 2008
PubMed
概括

失脂症中的阿波利波蛋白CIII (apoCIII) 通过激活蛋白激酶C-β (PKCbeta) 来损害血管内皮细胞中的胰岛素信号传递. 这导致内皮功能障碍和减少氧化的产生,导致动脉样硬化.

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