决策信心的神经相关性,计算和行为影响
Adam Kepecs1, Naoshige Uchida, Hatim A Zariwala
1Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, New York 11724, USA. kepecs@cshl.edu
Nature
|August 12, 2008
概括
大脑对决策信心的计算不是人类独有的. 动物的轨道前皮层神经元发出信心信号,驱动适应性行为,如等待奖励,这表明它在决策中发挥着基本作用.
科学领域:
- 神经科学是一个神经科学.
- 认知科学 认知科学
- 计算生物学 计算生物学
背景情况:
- 在不确定性下的决策在人类和动物中很常见.
- 了解信心估计的神经基础对于解释复杂行为至关重要.
- 目前的模型缺乏对大脑如何计算信心以及选择的洞察力.
研究的目的:
- 调查大脑如何计算决策信心.
- 为了探索在动物中基础的神经机制信心估计.
- 确定信任计算是否是决策的一个基本方面.
主要方法:
- 在执行气味分类任务的老鼠中进行行为分析和神经记录.
- 计算建模用于量化证据质量和预测信心.
- 操纵决策信心,通过改变刺激接近类别边界.
主要成果:
- 轨道前皮层神经元发射率与信心模型的预测非常相匹配.
- 其他机制,如刺激-结果关联学习,无法解释神经元活动.
- 小鼠等待奖励的意愿随着决策信心的增加而增加.
结论:
- 信心估计可以使用相对简单的神经操作来计算.
- 自信估计存在于动物大脑中,并影响行为,挑战了关于元认知的先前假设.
- 自信估计是跨物种决策的基本和无处不在的组成部分.
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