通过表型噪音介导的自我破坏性合作.
Martin Ackermann1, Bärbel Stecher, Nikki E Freed
1Institute of Integrative Biology, ETH Zurich, 8092 Zürich, Switzerland. martin.ackermann@env.ethz.ch
Nature
|August 23, 2008
概括
现型噪声允许合作细胞进化,即使合作是自我破坏性的. 这发生在具有更高自我毁灭概率的细胞获得更多资源时,就像在细菌感染中看到的那样.
科学领域:
- 进化生物学是进化的生物学.
- 微生物学 微生物学
- 遗传学 遗传学 是一个
背景情况:
- 在生物系统中的合作往往是一个挑战,特别是当合作是自我破坏的.
- 自毁性合作,其中个人在帮助他人时死亡,需要基因维护机制.
- 现型噪音是区分群体在自我破坏性合作中的潜在机制.
研究的目的:
- 通过表型噪音调解的自我破坏性合作的演变进行调查.
- 探索分类在合作演变中的作用.
- 检查这个模型与细菌病原发生的相关性.
主要方法:
- 在表型噪音和分类下合作的理论建模.
- 使用沙门氏菌Typhimurium进行实验验证.
主要成果:
- 自毁合作的杂表达可以在自毁概率较高的个体获得更大的公共商品 (品种) 访问时演变.
- 在空间结构化的环境中,可以产生分类.
- 现型噪音可以促进合作的子群体,促进感染.
结论:
- 杂地表达的自我破坏性合作行动可以在各种条件下演变.
- 自毁合作是表型噪音的一个合理的生物功能.
- 现型噪音介导的自我破坏性合作可能在细菌病原发生过程中发挥重要作用.
相关概念视频
Frequency-dependent Selection
20.2K
When the fitness of a trait is influenced by how common it is (i.e., its frequency) relative to different traits within a population, this is referred to as frequency-dependent selection. Frequency-dependent selection may occur between species or within a single species. This type of selection can either be positive—with more common phenotypes having higher fitness—or negative, with rarer phenotypes conferring increased fitness.
20.2K
Deindividuation
22.4K
Deindividuation is a form of social influence on an individual’s behavior such that the individual engages in unusual or non-normal behavior while in a group setting. Why? Because in these group settings, the individual no longer sees themselves as an individual anymore, disinhibiting their behavior and personal restraint.
22.4K
Coordination of Gene Expression Processes in Bacteria
1.1K
The DNA replication, transcription, and translation processes are intricately coupled in bacteria, allowing efficient gene expression and rapid protein synthesis. While this physical and functional coordination is advantageous, it introduces challenges that bacteria overcome through specific regulatory mechanisms.Coupling of Replication, Transcription, and TranslationThe coupling of replication, transcription, and translation is a hallmark of bacterial gene expression. As the replisome unwinds...
1.1K
Evolution of New Traits in Microbes
201
Microorganisms evolve rapidly due to their large population sizes and short generation times, often exhibiting measurable changes within days under laboratory conditions. Natural selection acts on standing genetic variation, enabling the retention and amplification of beneficial traits that confer fitness advantages in changing environments.Adaptive Pigment Regulation in RhodobacterIn Rhodobacter, a genus of purple non-sulfur bacteria, light-harvesting pigments such as bacteriochlorophyll and...
201
Microbial Interactions: Cooperation
63
Microbial cooperation involves beneficial interactions in which different species work together for individual or mutual advantage. These interactions can profoundly influence ecological dynamics and evolutionary processes, and they are essential to many pathogenic and symbiotic relationships.Nematode–Bacteria CooperationA striking example is the relationship between the Gram-negative bacterium Xenorhabdus nematophila and the parasitic nematode Steinernema carpocapsae. Juvenile nematodes...
63
Microbial Interactions: Competition
94
Microbial competition is an ecological interaction in which microorganisms vie for limited resources within shared environments. These resources may include nutrients, space, or light, depending on the system. The intensity and outcome of competition are influenced by the environmental context, such as nutrient availability, spatial constraints, and the diversity of microbial species present. These competitive interactions significantly influence the structure, function, and resilience of...
94


