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Updated: May 29, 2026

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确定ALK是主要的家族神经母细胞瘤倾向基因

Yaël P Mossé1, Marci Laudenslager, Luca Longo

  • 1Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.

Nature
|August 30, 2008
PubMed
概括

形淋巴瘤激酶 (ALK) 基因的生殖基因突变是遗传性神经母细胞瘤的主要原因. 激活ALK突变,无论是遗传的还是获得的,对于这种儿童癌症来说都是潜在的治疗标.

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