设计,合成和生物评估具有不同程度的分子复杂度的平坦西米辛类似物

K C Nicolaou1, Antonia F Stepan, Troy Lister

  • 1Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA. kcn@scripps.edu

概括

研究人员探索了白胺类类似物,发现酸部分对活性至关重要,但四环可以改变而不会失去抗生素功能.

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