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Updated: Jul 2, 2026

Radiolabeling and Quantification of Cellular Levels of Phosphoinositides by High Performance Liquid Chromatography-coupled Flow Scintillation
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Radiolabeling and Quantification of Cellular Levels of Phosphoinositides by High Performance Liquid Chromatography-coupled Flow Scintillation

Published on: January 6, 2016

通过Wnt3a介导的酸丁酸4,5-双酸盐的形成调节了LRP6的酸化

Weijun Pan1, Sun-Cheol Choi, He Wang

  • 1Department of Pharmacology, Yale University School of Medicine, New Haven, CT 06510, USA.

Science (New York, N.Y.)
|September 6, 2008
PubMed
概括

酸-4-酸5-激酶I型 (PIP5KI) 对于Wnt信号传输至关重要. Wnt3a激活了PIP5KI,它产生了脂 4,5-二酸盐[PtdIns (4,5) P2]来调节低密度脂蛋白受体相关蛋白6 (LRP6) 的酸化.

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