相关实验视频
Updated: Jul 1, 2026

04:31
Measurement of Metabolic Rate in Drosophila using Respirometry
Published on: June 24, 2014
代谢的计数器是代谢的计数器
Carla B Green1, Joseph S Takahashi, Joseph Bass
1Department of Biology, University of Virginia, Charlottesville, VA 22904, USA.
Cell
|September 9, 2008
概括
身体的内部时钟 (循环节律系统) 和新陈代谢是紧密联系在一起的. 破坏这种联系可以导致诸如肥胖和糖尿病之类的疾病.
科学领域:
- 生理学 生理学 生理学
- 代谢过程中的代谢.
- 时间生物学 时间生物学
背景情况:
- 昼夜系统组织生理过程,包括新陈代谢,与地球的24小时周期.
- 昼夜和代谢系统都是复杂的反网络,涉及中枢神经系统和外围组织.
研究的目的:
- 审查昼夜和代谢系统之间的复杂关系.
- 探索这种关系对心血管疾病,肥胖和糖尿病的影响.
主要方法:
- 关于昼夜节律和代谢平衡的现有研究的文献综述.
- 对调查昼夜调节和代谢信号之间的相互作用的研究进行分析.
主要成果:
- 循环节调节从根本上与代谢平衡有关.
- 昼夜节律的失调与各种疾病的发展有关.
- 代谢信号相互影响昼夜系统,影响基因表达和行为.
结论:
- 昼夜和代谢系统之间的双向通信对整体健康至关重要.
- 了解这种相互作用对于开发代谢和心血管疾病的治疗策略至关重要.
- 对昼夜和代谢失调的进一步研究可能为疾病预防和治疗提供新的见解.
相关概念视频
What is Metabolism?
Overview
Metabolic Rate
The human body is a powerhouse of energy, with every cell performing numerous functions that require energy. This energy production and consumption is measured by the metabolic rate, which quantifies the total heat generated by all the body's chemical reactions and mechanical work. This measurement helps to determine the rate of kilocalorie (kcal) consumption needed to fuel all ongoing activities.
The Basal Metabolic Rate (BMR) measures the energy expended at rest.
Several factors influence the...
The Basal Metabolic Rate (BMR) measures the energy expended at rest.
Several factors influence the...
Introduction to Metabolism
Metabolism encompasses all biochemical reactions in a living organism, facilitating both the breakdown and synthesis of biomolecules. These metabolic processes are categorized into catabolic and anabolic pathways, which operate in a coordinated manner to ensure energy balance and cellular function.Catabolic Pathways and Energy ReleaseCatabolic pathways involve the breakdown of complex macromolecules such as carbohydrates, lipids, and proteins into smaller structures like monosaccharides, fatty...
Overview of Metabolism
Living cells constantly carry out various chemical reactions which are necessary for their proper functioning. These reactions are interlinked to one another via multiple pathways. The collection of these chemical reactions is known as metabolism.
Plant Metabolism
Sunlight, the primary source of energy in plants, is first absorbed by the chlorophyll pigments present in their leaves. Plants then use this energy to carry out photosynthesis, where water is oxidized into oxygen and carbon dioxide...
Plant Metabolism
Sunlight, the primary source of energy in plants, is first absorbed by the chlorophyll pigments present in their leaves. Plants then use this energy to carry out photosynthesis, where water is oxidized into oxygen and carbon dioxide...
Regulation of Metabolism
Cellular needs and conditions vary from cell to cell and change within individual cells over time. For example, the required enzymes and energetic demands of stomach cells are different from those of fat storage cells, skin cells, blood cells, and nerve cells. Furthermore, a digestive cell works much harder to process and break down nutrients during the time that closely follows a meal compared with many hours after a meal. As these cellular demands and conditions vary, so do the amounts and...
Nonlinear Pharmacokinetics: Michaelis-Menten Equation
The Michaelis–Menten equation is a fundamental model for describing capacity-limited kinetics in drug metabolism. It offers insights into the rate of decline of plasma drug concentration Cp over time, with Vmax and KM as pivotal parameters.
Vmax represents the maximum achievable process rate, while KM, known as the Michaelis constant, signifies the drug concentration at which the process rate reaches half its maximum. This relationship between Vmax, KM, and Cp gives rise to three distinct...
Vmax represents the maximum achievable process rate, while KM, known as the Michaelis constant, signifies the drug concentration at which the process rate reaches half its maximum. This relationship between Vmax, KM, and Cp gives rise to three distinct...

