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Updated: May 6, 2026

Spatio-Temporal Manipulation of Small GTPase Activity at Subcellular Level and on Timescale of Seconds in Living Cells
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Published on: March 9, 2012

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冠状蛋白1B对抗皮质动蛋白,并重新塑造了lamellipodia中的含有Arp2/3的动蛋白分支

Liang Cai1, Alexander M Makhov, Dorothy A Schafer

  • 1Department of Cell and Developmental Biology, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7295, USA.

Cell
|September 9, 2008
PubMed
概括

冠状蛋白1B分解了lamellipodia中的Arp2/3-actin网络,这是细胞迁移必不可少的过程. 这种分解被Cortactin对抗,揭示了调节分支性actin动态的关键机制.

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Author Spotlight: Optogenetic Inhibition of Rho1-Mediated Actomyosin Contractility Coupled with Measurement of Epithelial Tension in Drosophila Embryos12:35

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Arp2/3 Complex
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