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在真核细胞中使用生物相容的化学诱导剂进行条件糖化

Jennifer L Czlapinski1, Michael W Schelle, Lawrence W Miller

  • 1Department of Chemistry, University of California, Berkeley, California 94720, USA.

Journal of the American Chemical Society
|September 16, 2008
PubMed
概括

一种新型的生物相容化学二元化诱导剂 (CID),Tmp-SLF,可以在没有不必要的副作用的情况下实现向蛋白质二元化. 这种新的CID成功调节了酵母中的基因表达,并为精确的生物控制设计了哺乳动物细胞.

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