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Sae2,Exo1和Sgs1在DNA双链断裂处理中进行合作

Eleni P Mimitou1, Lorraine S Symington

  • 1Department of Microbiology, Columbia University Medical Center, 701 West 168th Street, New York, New York 10032, USA.

Nature
|September 23, 2008
PubMed
概括

酵母 Exo1 核酶和 Sgs1 螺旋酶通过替代途径处理 DNA 双链断裂 (DSB). Sae2对于早期的DSB处理至关重要,Exo1和Sgs1在随后的步骤中起作用,产生同源重组的基质.

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