中国成年人高血压亚型和心血管疾病风险
Tanika N Kelly1, Dongfeng Gu, Jing Chen
1Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA 70112, USA.
Circulation
|September 24, 2008
概括
所有高血压亚型都显著增加了中国成年人心血管疾病的风险. 首要预防高血压对于这一群体的公共健康至关重要.
科学领域:
- 心脏病学 心脏病学
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 高血压是心血管疾病 (CVD) 的一个主要风险因素.
- 了解高血压亚型对心血管疾病风险的影响差异对于有针对性的预防策略至关重要.
- 中国成年人是高血压患病率和心血管疾病负担相当大的重要人口群体.
研究的目的:
- 研究不同高血压亚型与心血管疾病的发病率和死亡率之间的关联.
- 量化与综合性静脉 - 静脉高血压,孤立的静脉高血压,孤立的静脉高血压和治疗的高血压相关的风险.
- 为公共卫生倡议提供证据,重点关注中国的高血压管理.
主要方法:
- 一项前性队列研究,涉及169,871名40岁及以上的中国成年人.
- 1991年收集的系统血压 (SBP) 和透气血压 (DBP) 的基线数据.
- 1999-2000年进行的随访以确定心血管疾病发病率和死亡率,高血压亚型根据SBP/DBP值定义.
主要成果:
- 与正常血压患者相比,所有高血压亚型都与显著增加的心血管疾病发病率和死亡率有关.
- 综合性缩性和扩张性高血压显示,心血管疾病发病率 (2.73) 和死亡率 (2.53) 的相对风险最高.
- 孤立的静脉缩高血压 (RR发生率1.78,RR死亡率1.68) 和孤立的静脉缩高血压 (RR发生率1.59,RR死亡率1.45) 也存在重大风险.
结论:
- 所有已识别的高血压亚型都与中国成年人群中心血管疾病风险大幅增加有关.
- 这些发现强调了高血压作为公共卫生问题的重要性,需要采取初级预防措施.
- 实施有效的高血压预防和管理计划对于减少中国心血管疾病的负担至关重要.
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