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Updated: Jun 28, 2026

Visualization of DNA Repair Proteins Interaction by Immunofluorescence
07:55

Visualization of DNA Repair Proteins Interaction by Immunofluorescence

Published on: June 26, 2020

53BP1在V(D) J重组过程中促进了远程DNA末端连接

Simone Difilippantonio1, Eric Gapud, Nancy Wong

  • 1Experimental Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892-1360, USA.

Nature
|October 22, 2008
PubMed
概括

53BP1蛋白在淋巴细胞中V(D) J重组过程中对DNA修复至关重要. 缺少它会导致编码末端降解和基因组不稳定,导致T细胞缺陷和淋巴衰竭.

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Detection of Homologous Recombination Intermediates via Proximity Ligation and Quantitative PCR in Saccharomyces cerevisiae

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