心力衰竭是骨科骨折的危险因素:对16294名患者的基于人口的分析
Sean van Diepen1, Sumit R Majumdar, Jeffrey A Bakal
1Division of Cardiology, University of Alberta, Edmonton, Alberta, Canada.
Circulation
|October 22, 2008
概括
心力衰竭 (HF) 显著增加了骨科骨折的风险,特别是部骨折. 建议对心力衰竭患者进行早期查和骨质疏松症治疗,以减轻这种风险.
科学领域:
- 心脏病学 心脏病学
- 整形外科 整形外科 整形外科
- 老年学是一门学科.
背景情况:
- 心力衰竭 (HF) 与可能加速骨损失和增加骨折风险的因素有关.
- 脊髓炎和骨折风险增加之间的关联尚不清楚.
研究的目的:
- 调查心力衰竭 (HF) 的新诊断是否与骨科骨折风险增加有关.
- 为了确定患有HF的患者部骨折的特定风险.
主要方法:
- 一项基于人口的队列研究包括16294名65岁以上的患有心血管疾病的患者.
- 2,041名新的HF诊断患者与14,253名非HF心血管诊断的对照患者进行了比较.
- 主要结局是急诊室访问后一年内需要住院治疗的任何骨科骨折.
主要成果:
- 患有HF的患者在一年内有显著更高的骨科骨折发病率 (4.6%对1.0%,P<0.001).
- 关节骨折的风险在HF队列中也大大增加 (1.3%与0.1%,P<0.001).
- 经过调整后的分析显示,HF独立地与任何骨折风险增加4倍和部骨折风险增加6.3倍相关.
结论:
- 心力衰竭独立地与随后的骨科骨折,特别是关节骨折的风险显著增加有关.
- 这些发现强调了在被诊断为HF的患者中需要主动查和骨质疏松症管理的需要.
- 考虑HF患者的骨质疏松症查和治疗对于减少骨折风险至关重要.
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