移动视觉刺激的经验推动了皮质方向选择性的早期发展
Ye Li1, Stephen D Van Hooser, Mark Mazurek
1Department of Neurobiology, Duke University School of Medicine, Durham, North Carolina 27710, USA.
Nature
|October 24, 2008
概括
早期的视觉体验塑造了发育中的大脑. 的运动训练在视觉皮层迅速建立了方向选择性神经回路,证明了经验驱动的发展.
科学领域:
- 神经科学是一个神经科学.
- 发育神经科学的发展神经科学.
- 视觉系统开发 视觉系统开发
背景情况:
- 视觉皮层电路在出生后成熟,缺乏初始连接和响应选择性.
- 方向选择性反应对早期视觉丧失敏感,但发育机制尚不清楚.
研究的目的:
- 研究刺激驱动的神经活动如何引导皮质方向选择性的出现.
- 为了监测运动体验对视觉上天真的子发展方向选择性反应的影响.
主要方法:
- 在视觉上天真的身上使用运动训练协议.
- 采用了内在信号成像和双光子成像技术.
- 评估神经活动和空间组织的方向偏好.
主要成果:
- 运动训练导致特定皮层区域的方向柱迅速出现.
- 单个神经元在训练后表现出加强的方向选择性反应和增加的局部连贯性.
- 使用移动刺激进行训练,与闪刺激不同,增强方向选择性.
结论:
- 对移动视觉刺激的早期经验对于视觉皮层中方向选择性反应的快速出现至关重要.
- 发育过程中的神经活动模式是由特定的视觉体验塑造的.
- 经验提炼神经回路,以建立功能视觉处理能力.
相关概念视频
Vision
Vision is the result of light being detected and transduced into neural signals by the retina of the eye. This information is then further analyzed and interpreted by the brain. First, light enters the front of the eye and is focused by the cornea and lens onto the retina—a thin sheet of neural tissue lining the back of the eye. Because of refraction through the convex lens of the eye, images are projected onto the retina upside-down and reversed.
Motor and Sensory Areas of the Cortex
The cerebral cortex, the brain's outermost layer, is pivotal in processing complex cognitive tasks, emotions, and various sensory inputs and executing voluntary motor activities. This intricate structure is divided into three primary functional areas: the motor areas, sensory areas, and association areas.
Motor Areas
The motor areas located in the frontal lobe are central to controlling voluntary movements. This region is further subdivided into the primary motor cortex and the premotor cortex.
Motor Areas
The motor areas located in the frontal lobe are central to controlling voluntary movements. This region is further subdivided into the primary motor cortex and the premotor cortex.
Visual System
Light enters the eye through the cornea, a transparent, dome-shaped surface covering the surface of the eyeball that helps to direct and focus incoming light. This light is then channeled toward the pupil, an adjustable opening whose size is controlled by the iris. The iris, a pigmented muscle, regulates the amount of light entering the eye by contracting or dilating the pupil, thereby ensuring optimal light levels for clear vision.
Once through the pupil, the light passes through the lens, a...
Once through the pupil, the light passes through the lens, a...


