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Published on: July 4, 2007

奥戈巴拉·杜姆博:在非洲建立疟疾研究能力

Stephen Pincock1

  • 1stephen.pincock@journalist.co.uk

Lancet (London, England)
|November 6, 2008
PubMed
概括

No abstract available in PubMed .

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Malaria pathogenesis in humans reflects a delicate interplay between parasite biology and host response. Clinical illness reflects a host’s immune response to the parasite’s asexual replication cycle, which is often asymptomatic in individuals with partial immunity. From the parasite's perspective, transmission between mosquito and human with minimal host pathology is evolutionarily advantageous. Among the six Plasmodium species infecting humans, P. falciparum and P. vivax dominate in global...