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Updated: Jun 28, 2026

Chromatin Isolation by RNA Purification (ChIRP)
11:09

Chromatin Isolation by RNA Purification (ChIRP)

Published on: March 25, 2012

空气非编码RNA通过准G9a到染色质来表观遗传地沉默转录

Takashi Nagano1, Jennifer A Mitchell, Lionel A Sanz

  • 1Laboratory of Chromatin and Gene Expression, Babraham Institute, Babraham Research Campus, Cambridge CB22 3AT, UK. takashi.nagano@bbsrc.ac.uk

Science (New York, N.Y.)
|November 8, 2008
PubMed
概括

像空气这样的大型非编码RNAs (ncRNAs) 在表观遗传学上沉默基因. 空气招募G9a酶以使小鼠胎盘中的Slc22a3基因表达沉默,揭示了表观遗传基因沉默的机制.

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