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Updated: Jun 28, 2026

Wild-type Blocking PCR Combined with Direct Sequencing as a Highly Sensitive Method for Detection of Low-Frequency Somatic Mutations
10:41

Wild-type Blocking PCR Combined with Direct Sequencing as a Highly Sensitive Method for Detection of Low-Frequency Somatic Mutations

Published on: March 29, 2017

化SERS:一种用于区分DNA序列中的突变的新方法.

Sumeet Mahajan1, James Richardson, Tom Brown

  • 1School of Chemistry, University of Southampton, Southampton SO17 1BJ, United Kingdom.

Journal of the American Chemical Society
|November 14, 2008
PubMed
概括

这项研究引入了一种新的表面增强拉曼光谱法 (SERS) 方法来检测遗传变异. 该技术准确地识别高灵敏度的DNA中的突变和单核酸多态 (SNP).

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