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减肥手术后的怀孕和生育能力:一个系统的审查
Melinda A Maggard1, Irina Yermilov, Zhaoping Li
1Rand Corporation, Santa Monica, California, USA. mmaggard@mednet.ucla.edu
JAMA
|November 20, 2008
概括
在生育年龄的女性中,腹部外科手术的数量正在增加. 减肥手术后的怀孕可能会导致较少的不良孕妇和新生儿后果,与没有手术的肥胖女性相比.
科学领域:
- 生殖健康 生殖健康
- 外科手术的结果
- 孕产妇和胎儿医学 孕产妇和胎儿医学
背景情况:
- 腹腔外科手术的使用量显著增加,特别是在生育年龄的女性中.
- 这一趋势需要了解对怀孕和生育能力的影响.
研究的目的:
- 为了估计18-45岁妇女的减肥手术率.
- 审查关于怀孕和生育能力结果的现有文献.
主要方法:
- 搜索了主要的数据库 (Medline,EMBASE,Cochrane) 来查找1985-2008年的研究.
- 包括75篇分析生育,营养,孕产妇和新生儿结局的文章.
- 利用全国性住院患者样本数据 (1998-2005) 来估计手术率.
主要成果:
- 18-45岁的女性占减肥手术患者的49%.
- 研究表明,与肥胖对照人群相比,减肥手术后的孕产妇并发症率 (妊娠期糖尿病,孕前) 较低.
- 新生儿结局在手术后与肥胖对照相比类似或有所改善.
结论:
- 减肥手术后的怀孕可能与与肥胖女性相比,减少了对母亲和新生儿的不良结果.
- 需要进一步进行高质量的研究来证实这些发现.
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