Jove
Visualize
联系我们

相关概念视频

Stress: General Loading Conditions01:15

Stress: General Loading Conditions

To grasp the intricacy of real-world conditions where multiple loads are applied simultaneously to a structure, one might visualize a section passing through a specific point within a body, aligned parallel to the xy plane. This section is subjected to various forces, including original loads, normal forces, and shearing forces.
The shearing force, possessing potential directionality within the plane of the section, is simplified into two component forces running parallel to the x and y axes.
Stress Concentrations01:13

Stress Concentrations

The concept of stress concentration is crucial for understanding how materials respond under bending stresses, particularly when there are irregularities or discontinuities in the material's geometry. Normally, stress in a symmetric member subjected to pure bending is assumed to be uniformly distributed across the entire cross-section. However, this assumption does not hold when there are variations in the cross-sectional geometry or the presence of notches and holes.
The stress concentration...
Stress Concentrations01:24

Stress Concentrations

Stress concentration is when stress intensifies near discontinuities such as holes or abrupt cross-sectional changes in a structural member. This localized stress can often surpass the average stress within the member. The stress distribution in flat bars, either with a circular hole or varying widths connected by fillets, can be determined experimentally using a photoelastic method. The results are based on ratios of geometric parameters like the ratio of the hole's radius to the smaller width...
Stress on an Oblique Plane01:16

Stress on an Oblique Plane

Understanding stress on an oblique plane under axial loading is pivotal in material mechanics. This analysis offers insight into a material's durability and strength, which is crucial for civil engineering and structural design. Axial loading refers to force application along the material's central axis, causing compression or elongation and leading to normal stress. Normal stress occurs when a force acts perpendicularly to the material's area, resulting in compressive or tensile stress. When...
Principal Stresses01:24

Principal Stresses

The graphical depiction of normal and shearing stress equations is represented by a circle, demonstrating the interplay between these stresses under different angular conditions. The center of this circle C, located on the vertical axis, represents the average normal stress, while its radius shows the range of stress variations. At points A and B, where the circle intersects the horizontal axis, the maximum and minimum normal stresses are observed, occurring without shearing stress. These...
Stress01:20

Stress

When a force is applied on a body, it undergoes deformation. In order to restore the body to its original shape and/or size, an opposite or restoring force is generated within the body. This restoring force is equal to the magnitude of the applied force, but acts in the opposite direction. The amount of this restoring force developed per unit area of the body is called stress. Stress is a tensor quantity and has the SI unit pascal. Stress can be separated into four broad categories depending...

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Pairwise transmembrane domain insertion during multipass protein biogenesis.

Molecular cell·2026
Same author

Design principles of human membrane protein topology.

The Journal of cell biology·2026
Same author

Value of TERT Promoter Mutations for Early Outcomes in Papillary Thyroid Cancer.

Endocrine-related cancer·2026
Same author

Checking in on proteostasis.

Nature structural & molecular biology·2026
Same author

Recent advances in single-port robotic thyroidectomy: evolution, techniques, and clinical outcomes.

Annals of surgical treatment and research·2026
Same author

Comparison of <sup>18</sup>F-Choline PET/CT and <sup>99m</sup>Tc-Sestamibi SPECT/CT in the Localization of Hyperactive Parathyroid Glands in Primary Hyperparathyroidism: Diagnostic Performance in Discordant Cases.

Frontiers in endocrinology·2025
Same journal

A viral ORFeome library for systems-level genetic dissection of host-pathogen interactions.

Cell·2026
Same journal

Co-option of lysosomal machinery shapes the evolution of the intracellular photosymbiosis supporting coral reefs.

Cell·2026
Same journal

LEF1 and niche factors determine T cell stemness across chronic diseases.

Cell·2026
Same journal

Recurrent patterns of TOP1-mediated neuronal genomic damage shared by major neurodegenerative disorders.

Cell·2026
Same journal

Four-dimensional molecular mapping from a spatial snapshot reveals the dynamics of hair follicle organogenesis.

Cell·2026
Same journal

Whole-cell particle-based digital twin simulations from 4D lattice light-sheet microscopy data.

Cell·2026
查看所有相关文章
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关实验视频

Updated: Jun 27, 2026

Method for the Assessment of Effects of a Range of Wavelengths and Intensities of Red/near-infrared Light Therapy on Oxidative Stress In Vitro
08:16

Method for the Assessment of Effects of a Range of Wavelengths and Intensities of Red/near-infrared Light Therapy on Oxidative Stress In Vitro

Published on: March 21, 2015

照亮了紧张的急救中心.

Sang-Wook Kang1, Ramanujan S Hegde

  • 1National Institutes of Health, Bethesda, MD 20892, USA.

Cell
|December 2, 2008
PubMed
概括
此摘要是机器生成的。

研究人员使用一种特殊的光蛋白来观察酵母体内 плазма内网膜 (ER). 这有助于他们了解ER如何在压力期间处理蛋白质的生产和成熟.

更多相关视频

Integrating Visual Psychophysical Assays within a Y-Maze to Isolate the Role that Visual Features Play in Navigational Decisions
07:09

Integrating Visual Psychophysical Assays within a Y-Maze to Isolate the Role that Visual Features Play in Navigational Decisions

Published on: May 2, 2019

相关实验视频

Last Updated: Jun 27, 2026

Method for the Assessment of Effects of a Range of Wavelengths and Intensities of Red/near-infrared Light Therapy on Oxidative Stress In Vitro
08:16

Method for the Assessment of Effects of a Range of Wavelengths and Intensities of Red/near-infrared Light Therapy on Oxidative Stress In Vitro

Published on: March 21, 2015

Integrating Visual Psychophysical Assays within a Y-Maze to Isolate the Role that Visual Features Play in Navigational Decisions
07:09

Integrating Visual Psychophysical Assays within a Y-Maze to Isolate the Role that Visual Features Play in Navigational Decisions

Published on: May 2, 2019

科学领域:

  • 细胞生物学 细胞生物学
  • 分子生物学分子生物学
  • 生物化学 生物化学

背景情况:

  • 维持内质网膜 (ER) 稳态对于细胞功能至关重要.
  • 蛋白质成熟和蛋白质流量必须在ER中保持平衡.
  • 在这些过程中,ER的内部环境起着关键作用.

研究的目的:

  • 研究ER环境对细胞干扰的动态反应.
  • 开发和使用一种新的方法来监测活细胞中的ER氧化还原状态.
  • 了解如何在蛋白质负载的不同条件下保持ER平衡.

主要方法:

  • 在Saccharomyces cerevisiae (酵母菌) 中利用了基因编码的氧化回归敏感光蛋白 (roGFP).
  • 采用活细胞成像技术来监测ER氧化还原潜力.
  • 引入了特定的干扰来改变蛋白质流量和ER压力.

主要成果:

  • 证明了ER氧化还原环境的实时变化,以应对不同的干扰.
  • 在ER氧化还原状态与蛋白质成熟能力相关的变化.
  • 提供了对ER的适应机制的见解.

结论:

  • 在ER氧化还原环境是一个动态参数,它响应蛋白质的流量.
  • 监测ER氧化还原状态为研究ER恒温提供了一种有价值的方法.
  • 这项研究揭示了ER在压力下适应和维持功能的能力.