在实施快速反应小组之前和之后,全医院的代码率和死亡率
Paul S Chan1, Adnan Khalid, Lance S Longmore
1Division of Cardiology, Mid America Heart Institute and University of Missouri, Kansas City, MO 64111, USA. pchan@cc-pc.com
JAMA
|December 4, 2008
概括
在这项研究中,快速反应小组没有降低整体医院心脏骤停或死亡率. 虽然非重症监护单位的代码率下降,但对患者的整体影响仍然不确定.
科学领域:
- 医学成果研究研究成果
- 医院质量改善 医院质量改善
- 患者安全 患者安全
背景情况:
- 众所周知,快速反应小组 (RRT) 在重症监护室 (ICU) 外的成年住院患者中降低心肺骤停 (代码) 率.
- 对整体全医院代码率和死亡率的RRT的影响不太清楚,因为一个关键的RRT功能涉及将患者转移到ICU.
研究的目的:
- 评估长期快速反应小组干预对全医院代码率和死亡率的有效性.
- 为了确定RRT的实施是否会导致整个医院的关键事件和死亡减少.
主要方法:
- 一项前性队列研究在一家404张床位的高等学术医院进行.
- 分析了RRT实施前 (2004年1月至2005年8月) 24,193次入院和 (2006年1月至2007年8月) 后24978次入院的数据.
- 一个由3名成员组成的RRT,包括ICU工作人员和呼吸治疗师,对急性生理衰退的患者做出了反应.
主要成果:
- 在RRT实施后,全医院的代码率从11.2下降到每1000例入院7.5下降,但这对于主要终点 (AOR,0.76;P = .06) 没有达到统计学意义.
- 观察到非ICU代码率显著降低 (AOR,0.59;P = .03相互作用),而ICU代码率没有显著变化 (AOR,0.95).
- 整个医院的死亡率在干预前 (3.22%) 和干预后 (3.09%) 保持相似 (AOR,0.95;P = .52).
结论:
- 在这项单一机构研究中,快速反应小组的实施与整体医院范围的代码率或死亡率的显著降低无关.
- 虽然非ICU代码率有所改善,但对关键事件和死亡率的整体影响需要进一步调查.
- 在二次分析中,RRT的潜在治疗不足或使用不足可能影响了观察到的死亡率结果.
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