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通过单个人类黑色素瘤细胞有效形成瘤

Elsa Quintana1, Mark Shackleton, Michael S Sabel

  • 1Howard Hughes Medical Institute, Life Sciences Institute, Department of Internal Medicine, and Center for Stem Cell Biology, University of Michigan, Ann Arbor, Michigan 48109-2216, USA.

Nature
|December 5, 2008
PubMed
概括

人类黑色素瘤细胞中的瘤起源潜力是常见的,而不是罕见的. 使用高度免疫受损的小鼠进行修改的异种移植试验显示,高达27%的黑色素瘤细胞可以形成瘤,这挑战了之前的估计.

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