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在体内通过PD-1阻断增强SIV特异性免疫力

Vijayakumar Velu1, Kehmia Titanji, Baogong Zhu

  • 1Emory Vaccine Center, Emory University School of Medicine, Atlanta, Georgia 30322, USA.

Nature
|December 17, 2008
PubMed
概括

在感染猿类免疫缺陷病毒 (SIV) 的中阻断编程死亡1 (PD-1) 改善了免疫反应,并减少了病毒载量. 这种方法增强了T细胞和抗体免疫力,为人类免疫缺陷病毒 (HIV) 感染提供了潜在的治疗方法.

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Tumor Immunotherapy01:27

Tumor Immunotherapy

Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.