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RNAi Screening for Host Factors Involved in Vaccinia Virus Infection using Drosophila Cells
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在Giardia lamblia的抗原变异是由RNA干扰调节的

César G Prucca1, Ileana Slavin, Rodrigo Quiroga

  • 1Laboratorio de Bioquímica y Biología Molecular, Facultad de Medicina, Universidad Católica de Córdoba, Córdoba X5004ASK, Argentina.

Nature
|December 17, 2008
PubMed
概括

吉亚迪亚寄生虫通过切换表面蛋白质,通过使用抗原变异来逃避免疫反应. 这项研究揭示了RNA干扰机制调节了这个开关,控制了哪种变异特异性表面蛋白 (VSP) 的表达.

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