身体质量指数和剧烈的体力活动以及男性心力衰竭的风险
Satish Kenchaiah1, Howard D Sesso, J Michael Gaziano
1Physicians' Health Study, Brigham and Women's Hospital, Boston, MA 02215, USA. skenchaiah@rics.bwh.harvard.edu
Circulation
|December 24, 2008
概括
体重指数 (BMI) 升高会增加心力衰竭 (HF) 的风险,即使在超重范围. 然而,强烈的体力活动显著降低了男性的HF风险.
科学领域:
- 心脏病学 心脏病学
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 肥胖 (BMI ≥30 kg/m2) 是心力衰竭 (HF) 的已知危险因素.
- 超重 (BMI 2529.9 kg/m2) 和体力活动对HF风险的影响仍然不太清楚.
研究的目的:
- 研究身体质量指数 (BMI) 和剧烈体力活动对心力衰竭 (HF) 发生率的独立和联合影响.
主要方法:
- 来自医生健康研究 (19822007) 的21,094名男性的前性队列研究.
- 体重指数 (BMI) 持续和明确地评估;强烈的体力活动分化 (活跃与不活跃).
- 用于调整混因素和评估高频风险的多变量分析.
主要成果:
- 每增加1kg/m2的BMI与11%的高风险增加有关.
- 与瘦身男性相比,超重和肥胖男性的HF风险明显更高 (分别增加49%和180%) .
- 剧烈的体力活动与HF风险降低18%有关;没有观察到BMI和活动之间的相互作用.
结论:
- 增加的BMI,包括超重/预肥的范围,与心力衰竭风险增加有关.
- 强烈的体力活动显示出对心力衰竭的保护作用.
- 促进健康体重和身体活动的公共卫生倡议对于减轻心力衰竭发病率至关重要.
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