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Bacterial Phylum Spirochaetes
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通过DDB1-DDB2复合体识别UVDNA损伤的结构基础

Andrea Scrima1, Renata Konícková, Bryan K Czyzewski

  • 1Friedrich Miescher Institute for Biomedical Research, Maulbeerstrasse 66, CH 4058 Basel, Switzerland.

Cell
|December 27, 2008
PubMed
概括

DDB1-DDB2复合体使用独特的结构机制检测UVDNA损伤. 这个过程涉及DDB2头发针,它精确地探测和结合光损伤,使得难以检测的DNA损伤.

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