2+) /卡尔莫杜林调节了白酸介导的植物免疫
Liqun Du1, Gul S Ali, Kayla A Simons
1Center for Integrated Biotechnology and Department of Horticulture, Washington State University, Pullman, Washington 99164-6414, USA.
Nature
|January 6, 2009
概括
(Ca2+) 信号调节植物病原体相互作用期间的酸水平. 卡2+/卡尔莫杜林结合转录因子AtSR1通过抑制EDS1的表达,作为植物免疫的负调节剂.
科学领域:
- 植物免疫力 植物免疫力
- 分子植物病理学
- 信号传递的.
背景情况:
- 植物病原体相互作用触发细胞内过渡物,对抗性至关重要.
- 酸对植物免疫反应至关重要,但其通过信号的调节仍然不清楚.
研究的目的:
- 阐明连接 (Ca2+) 信号与酸介导植物免疫的机制.
- 确定参与这一调节途径的关键分子参与者.
主要方法:
- 研究了阿拉比多普西斯AtSR1 (CAMTA3) 的功能丧失等位基因.
- 进行了对突变物影响酸积累和抗病能力的表皮病分析.
- 使用分子生物学技术分析了AtSR1与EDS1促进体的相互作用.
主要成果:
- 在AtSR1中失去功能的突变导致了构成性疾病耐药性和升高的酸水平.
- AtSR1直接与EDS1促进体结合,并抑制其表达.
- 对AtSR1的Ca2+/calmodulin结合是其抑制植物防御功能的必要条件.
结论:
- 一个新的调节途径通过AtSR1和EDS1.1,将Ca2+信号与酸水平连接起来.
- AtSR1作为植物免疫的负调节剂,将信号与酸介导的防御联系起来.
- 结合Ca2+/calmodulin对于AtSR1在调节植物防御反应中的作用至关重要.
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