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总合成和评价的异-二甲素SA和异-亚泰克素SA

Karen S MacMillan1, Trinh Nguyen, Trihn Nguyen

  • 1Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA.

Journal of the American Chemical Society
|January 22, 2009
PubMed
概括

研究人员合成了新的二甲胺类同类物,即异二甲胺SA和异亚甲胺,具有改变的化子单元. 这些化合物显示出强大的DNA化和细胞毒性,为天然产品药物设计提供了洞察力.

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