左心室功能和运动能力
Jasmine Grewal1, Robert B McCully, Garvan C Kane
1Division of Cardiovascular Diseases, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA.
JAMA
|January 22, 2009
概括
左心室透静功能障碍显著降低了运动能力,独立于缩功能. 这种关联随着年龄的增长和女性更为明显,突出显示了透缩功能.
科学领域:
- 心脏病学 心脏病学
- 心声回声扫描 (Echocardiography) 是一种心声回声扫描.
- 运动生理学 运动生理学
背景情况:
- 关于左心室功能对运动能力的预测值的数据有限.
- 调查这种关系中的年龄和性别相关差异至关重要.
研究的目的:
- 评估心声图学测定心脏功能的对运动能力的影响.
- 为了确定性别和年龄是否会改变这些关联.
主要方法:
- 对2867名接受运动心声扫描 (布鲁斯方案) 的患者进行横截面研究.
- 使用2D和多普勒技术评估左心室的抽缩和放缩功能.
- 排除患有缺血症,低射出率或显著的膜疾病的患者.
主要成果:
- 扩张性功能障碍与运动能力 (METs) 有着强烈且反向的相关性.
- 中度/重度透析功能障碍减小容量-1.30METs;轻度功能障碍 -0.70METs.
- 正常的缩功能变化没有影响容量;升高的填充压力 (E/e' ≥15) 将容量减少了-0.41 METs.
- 年龄,女性性别和肥胖 (BMI > 30) 是运动能力的独立负面预测因素.
结论:
- 左心室扩张性功能障碍是没有缺血症的患者运动能力降低的独立预测因素.
- 调查结果强调了透缩功能评估在运动能力评估中的重要性.
相关概念视频
Pathophysiology of Cardiac Performance
2.2K
Typical heart performance is influenced by heart rate, rhythm, myocardial contraction, and metabolism or blood flow. The cardiac muscle exhibits distinct electrophysiological features, including pacemaker activity and calcium channel control, which play a vital role in the heart's response to various drugs. The autonomic nervous system, comprising the sympathetic and parasympathetic branches, regulates heart rate. Sympathetic activation increases heart rate, while parasympathetic activation...
2.2K
Overview of the Heart
32.2K
The heart, a muscular organ located in the chest, functions as the body's pump, circulating blood through the vascular system. It has four chambers: two atria on top and two ventricles below. The right atrium receives deoxygenated blood from the body and passes it to the right ventricle, which pumps it to the lungs for oxygenation. The left atrium receives oxygenated blood from the lungs and transfers it to the left ventricle, which pumps it to the rest of the body.
The heart's structure...
The heart's structure...
32.2K
Exercise and Cardiac Output
3.8K
Regular physical activity is essential for maintaining cardiovascular health, with aerobic exercises being particularly effective. According to the American Heart Association, 150 minutes of moderate to intense aerobic exercise per week is recommended for a healthy heart. Aerobic activities may include brisk walking, running, bicycling, cross-country skiing, and swimming, ideally performed three to five times per week.
Sustained exercise increases the muscles' oxygen demand, which can be...
Sustained exercise increases the muscles' oxygen demand, which can be...
3.8K
Imbalances in Cardiac Output
3.3K
The heart's primary function is to pump blood throughout the body, maintaining a balance between blood sent out (cardiac output) and blood returning (venous return). If this balance is disrupted, it can result in congestive heart failure (CHF), a severe condition where the heart becomes an inefficient pump, leading to inadequate blood circulation.
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send...
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send...
3.3K
Exercise and Cardiovascular Response
6.7K
Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
6.7K
Physiology of the Heart: The Cardiac Cycle
15.9K
The cardiac cycle describes the events from one heartbeat to the next. It includes three main phases: diastole, atrial systole, and ventricular systole, all driven by changes in chamber pressures and the function of heart valves.
Diastole: The Relaxation Phase
During diastole, all four heart chambers relax. The atrioventricular (AV) valves open, and the semilunar valves close. This phase sees the lowest chamber pressures, promoting ventricular filling. Venous blood enters the heart through the...
Diastole: The Relaxation Phase
During diastole, all four heart chambers relax. The atrioventricular (AV) valves open, and the semilunar valves close. This phase sees the lowest chamber pressures, promoting ventricular filling. Venous blood enters the heart through the...
15.9K


