二色基因组和草的多样化
Andrew H Paterson1, John E Bowers, Rémy Bruggmann
1Plant Genome Mapping Laboratory, University of Georgia, Athens, Georgia 30602, USA. paterson@uga.edu
Nature
|February 4, 2009
概括
Sorghum bicolor (L.) Moench基因组分析显示,其庞大的尺寸是由于逆转移体. 基因分布和最近的重复可能解释了它的干旱耐受性.
科学领域:
- 植物基因组学 植物基因组学
- 生物信息学是一种生物信息学.
- 农业科学 农业科学
背景情况:
- (Sorghum bicolor) 是粮食,料,纤维和燃料的重要作物.
- 了解其基因组对于作物改进和农业应用至关重要.
研究的目的:
- 为了呈现Sorghum双色球基因组的初步分析.
- 将基因映射到它们的染色体位置,并了解基因组结构.
- 调查导致的基因组大小和耐旱性因素.
主要方法:
- 索尔古姆双色球基因组的全基因组猎枪测序.
- 使用遗传,物理和合成映射信息进行验证.
- 与米等相关物种进行比较的基因组学.
主要成果:
- 大约98%的基因被放置在它们的染色体上下文.
- 遗传重组仅限于大约三分之一的基因组.
- 与大米相比,逆转移素在异色染色体中的积累解释了较大的基因组大小.
- 大多数重复的基因组在米分歧之前就失去了一个成员.
- 24%的基因是草特异性的,7%是特异性的.
- 最近的基因和microRNA重复可能会赋予干旱耐受性.
结论:
- Sorghum 双色球基因组结构的特点是重组复原的异色素和保存的基因分布自古聚化以来.
- 包括microRNA在内的特定基因重复是的显著干旱耐受性的潜在贡献者.
- 这种基因组洞察力为未来对作物改良的研究提供了基础.
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