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Updated: Jun 25, 2026

Sequence-specific and Selective Recognition of Double-stranded RNAs over Single-stranded RNAs by Chemically Modified Peptide Nucleic Acids
09:04

Sequence-specific and Selective Recognition of Double-stranded RNAs over Single-stranded RNAs by Chemically Modified Peptide Nucleic Acids

Published on: September 21, 2017

在PNA-Ce(IV) /EDTA组合的目标序列识别中,高保真度的起源是作为选择性DNA切割器的位置选择性切割器

Yoshitaka Miyajima1, Takumi Ishizuka, Yoji Yamamoto

  • 1Research Center for Advanced Science and Technology, The University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo 153-8904, Japan.

Journal of the American Chemical Society
|February 10, 2009
PubMed
概括

人工限制DNA切割器 (ARCUT) 使用核酸 (PNA) 进行精确的DNA向. 不匹配显著降低了ARCUT的效率,强调了沃森-克里克对配对对序列识别的重要性.

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