关于HIV抗体咨询和测试对风险行为影响的证据
D L Higgins1, C Galavotti, K R O'Reilly
1Division of STD/HIV Prevention, Centers for Disease Control, Atlanta, GA 30333.
JAMA
|November 6, 1991
概括
艾滋病毒抗体咨询和测试显示,同性恋男性和静脉注射药物使用者的风险行为减少. 对孕妇的证据有限,但显示异性恋夫妇与感染者伴侣的风险降低.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 行为科学 行为科学
背景情况:
- 人类免疫缺陷病毒 (HIV) 抗体咨询和测试是关键干预措施.
- 了解对风险行为的影响对于预防策略至关重要.
研究的目的:
- 审查关于艾滋病毒抗体咨询和测试对行为影响的证据.
- 专注于各种人群,包括同性恋男性,静脉注射药物使用者,孕妇和异性恋者.
主要方法:
- 发表的摘要,期刊文章和会议演讲 (1986-1990) 的系统审查.
- 纳入50项研究,排除16项研究,因为方法上的缺陷.
- 基于样本选择,比较组和统计学意义的研究评估.
主要成果:
- 对同性恋男性的长度研究表明,测试后风险行为减少.
- 治疗中的静脉注射药物使用者显示药物使用和性风险行为减少.
- 在异性恋夫妇中观察到显著的风险降低,其中一个感染者是异性恋伴侣;对于孕妇的证据有限.
结论:
- 艾滋病毒咨询和检测表明,在特定人群中,有可能改变风险行为.
- 需要进一步的研究来探索各种环境和人口统计学方面的行为后果.
相关概念视频
Retrovirus Life Cycles
Retroviruses have a single-stranded RNA genome that undergoes a special form of replication. Once the retrovirus has entered the host cell, an enzyme called reverse transcriptase synthesizes double-stranded DNA from the retroviral RNA genome. This DNA copy of the genome is then integrated into the host’s genome inside the nucleus via an enzyme called integrase. Consequently, the retroviral genome is transcribed into RNA whenever the host’s genome is transcribed, allowing the retrovirus to...
Sexually Transmitted Infections
Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
Pulmonary Tuberculosis I
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast, controlled...
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast, controlled...
Amebiasis
Entamoeba histolytica, a protozoan parasite, is responsible for intestinal and extraintestinal amebiasis. Though a significant proportion of infections remain asymptomatic, approximately 50 million individuals annually are estimated to present with clinical disease, resulting in up to 100,000 deaths globally. The disease burden is disproportionately high in regions with lower socioeconomic status, such as parts of India, Africa, Mexico, and Latin America.Etiology and TransmissionThe infective...


